<p><strong>产品属性 Product Attributes </strong></p> <p><strong>基本信息 </strong></p> 别名： Lysosome membrane protein 2;85 kDa lysosomal membrane sialoglycoprotein;LGP85;Lysosome membrane protein II;LIMP II;Scavenger receptor class B member 2;Scarb2<br/>规格: 10ug ; 50ug ; 500ug ; 1mg<br/>外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM Tris-Citrate, 0.3M NaCl, pH6.5.<br/>纯度: ≥95% as determined by reducing SDS-PAGE.<br/>储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. <p><strong>产品信息 </strong></p> 背景说明： Lysosome membrane protein II (LIMPII)，also known as SCARB2，is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined.Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment.The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction，deafness，and peripheral neuropathy.Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A，Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand，foot and mouth disease (HFMD).Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4)，also known as action myoclonus-renal failure syndrome (AMRF).Alternatively spliced transcript variants encoding different isoforms have been found for this gene.In addition，LIMPII also has been shown to bind thrombospondin-1，may contribute to the pro-adhesive changes of activated platelets during coagulation，and inflammation.<br/>来源： Human Cells<p><strong>其它标识</strong></p> 溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.<br/>内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. <p><strong>产品介绍 Product Introduction</strong></p> 暂无数据 <p><strong>注意事项 Considerations</strong></p> 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 <br/>2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 <br/>3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。