基因名:CCL5
英文全称:chemokine (C-C motif) ligand 5
别称:D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228
中文名称:趋化因子配体5
Uniprot:P13501
GeneID:6352
交叉反应(推测):Human Mouse Rat (Bovine Cat Horse Pig Dog Macaque)
氨基酸大小:10kDa
表达氨基酸:1-91aa
Background:This gene is one of several chemokine genes clustered on the q-arm of chromosome 17.Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide.This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils.It causes the release of histamine from basophils and activates eosinophils.This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells.It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.Alternative splicing results in multiple transcript variants that encode different isoforms
Application:Immunology research
Derived from:E.coli
Purification:NI-NTA affinity purification
Formulation:Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping:The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage:Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°c="" for="" 2-3="">
Reconstitution:Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity:Purity≥85% as determined by reducing SDS-PAGE.
规格:10ug, 50ug, 100ug, 1mg, 注意：
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