<p><strong>产品属性 Product Attributes </strong></p> <p><strong>基本信息 </strong></p> 别名： Carbonic anhydrase 12;Carbonate dehydratase XII;Carbonic anhydrase XII;CA-XII;CA12;Carbonate dehydratase XII;CAXII<br/>规格: 10ug ; 50ug ; 500ug ; 1mg<br/>外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.<br/>纯度: ≥95% as determined by reducing SDS-PAGE.<br/>储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. <p><strong>产品信息 </strong></p> 背景说明： Carbonic Anhydrase (CA) XII，also known as Car12 and CA12，is an extracellular enzyme involved in the regulation of the microenvironment acidity and tumor malignant phenotype，was originally identified as a protein overexpressed in some types of cancers.It has showed that CA XII is induced by hypoxia and oestrogen and expressed at high levels on various types of cancer.The enzyme is directly involved in tumour progression，and its inhibition has an anti-tumour effect.Apart from its role in carcinogenesis，the enzyme contributes to various other diseases like glaucoma and arteriosclerotic plaques，among others.CA XII is therefore regarded as promising target for specific therapies，and may be used as a novel prognostic marker in combination with histologic grade of the tumors.<br/>来源： Human Cells<p><strong>其它标识</strong></p> 溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.<br/>内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. <p><strong>产品介绍 Product Introduction</strong></p> 暂无数据 <p><strong>注意事项 Considerations</strong></p> 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 <br/>2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 <br/>3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。