<p><strong>产品属性 Product Attributes </strong></p> <p><strong>基本信息 </strong></p> 别名： T-Lymphocyte Activation Antigen CD86;Activation B7-2 Antigen;B70;BU63;CTLA-4 Counter-Receptor B7.2;FUN-1;CD86;CD28LG2<br/>规格: 10ug ; 50ug ; 500ug ; 1mg<br/>外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.<br/>纯度: ≥95% as determined by reducing SDS-PAGE.<br/>储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. <br/>运输条件： The product is shipped at ambient temperature.<p><strong>产品信息 </strong></p> 背景说明： The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production，by binding CD28 or CTLA-4.It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells，such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.Isoform 2 interferes with the formation of CD86 clusters，and thus acts as a negative regulator of T-cell activation.The protein interacts with MARCH8，human herpesvirus 8 MIR2 protein，adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.<br/>来源： Human cells<p><strong>其它标识</strong></p> 溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.<br/>内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. <p><strong>产品介绍 Product Introduction</strong></p> Recombinant Human CD86 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro247 is expressed with a 6His tag at the C-terminus. <p><strong>注意事项 Considerations</strong></p> 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 <br/>2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 <br/>3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。