Known as：Growth/differentiation factor 8;GDF-8;Myostatin;Mstn;Gdf8

Derived from：Human cells

Purity：Greater than 95% as determined by reducing SDS-PAGE.

Formulation：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Shipping：The product is shipped at ambient temperature.

Storage：Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months

Reconstitution：Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.

Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Endotoxin：Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Background：Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.