产品属性 Product Attributes

基本信息

英文名称: Anti-CD274(PE) Monoclonal Antibody

规格: 25T ; 100T

宿主: Mouse

克隆类型: Monoclonal Antibody

亚型: IgG2b，κ

交叉反应: Human

应用: FCM

稀释比例: FCM 5uL/Test.

抗体信息

靶标: CD274

别名: CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed cell death 1 ligand 1; Programmed death ligand 1; RGD1566211

背景说明: PD-L1，also known as CD274 or B7H1，stands for programmed cell death ligand 1. It is a type I transmembrane protein that is thought to repress immune responses by binding to its receptor (PD1)，thus inhibiting T-cell activation，proliferation，and cytokine production. It contains V-like and C-like immunoglobulin domains. PD-L1 expression is regulated by various cytokines，such as TNF-α or LPS (ISSN: 1848-7718). Increased expression of this protein in certain types of cancers，e.g.，renal cell carcinoma or colon cancer，correlates with poor prognosis.

Swiss Prot: Q9EP73

Gene ID: 60533

亚细胞定位: Cell membrane

其它标识

储存条件: Store at 4℃ in dark.Do not freeze.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。