<p><strong>产品属性 Product Attributes </strong></p> <p><strong>基本信息 </strong></p> 英文名称： Anti-SMC1A Polyclonal Antibody<br/>中文名称： 染色体结构维持蛋白质1抗体<br/>规格： 100ul ; 50ul<br/>宿主： Rabbit<br/>克隆类型： Polyclonal Antibody<br/>亚型： IgG<br/>交叉反应：： Mouse ; Rat ; Human<br/>应用： IHC ; WB<br/>稀释比例： WB 1:500-2000. IHC 1:10-100.<p><strong>抗体信息 </strong></p> 靶标： SMC1A<br/>别名： SMC1;SMCB;CDLS2;SB1.8;SMC1L1;DXS423E;SMC1alpha<br/>背景说明： Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.<br/>Swiss Prot： Q14683<br/>Gene ID： 8243<br/>亚细胞定位： Nucleus<br/>免疫原： Recombinant protein of human SMC1A<br/>理论分子量： 143kDa<p><strong>其它标识 </strong></p> 纯化方法： Affinity purification<br/>储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.<br/>储存条件： Store at -20℃. Avoid freeze / thaw cycles. <p><strong>产品介绍 Product Introduction </strong></p> 使用前请离心。如有问题请及时联系我们。<br/>Quick spin before use. If you have any questions, please contact us. <p><strong>注意事项 Considerations </strong></p> 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 <br/>2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 <br/>3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。