产品属性 Product Attributes

基本信息

英文名称：Anti-CD274(AF594) Monoclonal Antibody

中文名称：程序性死亡配体1（CD274）抗体

规格：25ug ; 100ug

宿主：Rabbit

克隆类型：Monoclonal Antibody

亚型：IgG

交叉反应：Mouse

应用：FCM

稀释比例：FCM 1×10^6 cells+0.25ug.

抗体信息

靶标：CD274：

别名：CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed cell death 1 ligand 1; Programmed death ligand 1; RGD1566211

背景说明：PD-L1, also known as CD274 or B7H1, stands for programmed cell death ligand 1. It is a type I transmembrane protein that is thought to repress immune responses by binding to its receptor (PD1), thus inhibiting T-cell activation, proliferation, and cytokine production. It contains V-like and C-like immunoglobulin domains. PD-L1 expression is regulated by various cytokines, such as TNF-α or LPS (ISSN: 1848-7718). Increased expression of this protein in certain types of cancers, e.g., renal cell carcinoma or colon cancer, correlates with poor prognosis.

Swiss Prot：Q9EP73

Gene ID：60533

亚细胞定位：Cell membrane

免疫原：Recombinant protein of mouse CD274

其它标识

纯化方法：Affinity purification

储存液：PBS with 0.09% sodium azide and 0.5% BSA.

储存条件：Store at 4℃ in dark.Do not freeze.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。