<p><strong>产品属性 Product Attributes </strong></p> <p><strong>基本信息 </strong></p> 英文名称： Anti-NOTCH1 Polyclonal Antibody<br/>中文名称： 跨膜受体蛋白Notch-1抗体<br/>规格： 100ul ; 50ul<br/>宿主： Rabbit<br/>克隆类型： Polyclonal Antibody<br/>亚型： IgG<br/>交叉反应：： Rat ; Human<br/>应用： IHC ; WB<br/>稀释比例： WB 1:500-2000. IHC 1:50-200.<p><strong>抗体信息 </strong></p> 靶标： NOTCH1<br/>别名： Notch 1 extracellular truncation, Notch 1 intracellular domain, hN1, Lin-12, LIN12, MIS6, Motch A, mT14, Neurogenic locus notch homolog protein 1, Neurogenic locus notch protein homolog, NICD, Notch1 intracellular domain, NOTC1_HUMAN, Notch 1, NOTCH, Notch gene homolog 1 (Drosophila), Notch homolog 1 translocation associated (Drosophila), Notch homolog 1, translocation-associated (Drosophila), NOTCH, Drosophila, homolog of, 1, notch1, p300, TAN 1, TAN1, TAN1, Translocation Associated Notch Homolog, Translocation Associated Notch Homolog, Translocation associated notch protein TAN 1, Translocation-associated notch protein TAN-1<br/>背景说明： This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.<br/>Swiss Prot： P46531<br/>Gene ID： 4851<br/>亚细胞定位： Cytoplasm Nucleus<br/>免疫原： A synthetic peptide of human NOTCH1<br/>理论分子量： 273kDa<p><strong>其它标识 </strong></p> 纯化方法： Affinity purification<br/>储存液： pH7.4 PBS，0.05% NaN3，40% Glycerol.<br/>储存条件： Store at -20℃. Avoid freeze/thaw cycles. <p><strong>产品介绍 Product Introduction </strong></p> 使用前请离心。如有问题请及时联系我们。<br/>Quick spin before use. If you have any questions, please contact us. <p><strong>注意事项 Considerations </strong></p> 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 <br/>2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 <br/>3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。