<p><strong>产品属性 Product Attributes </strong></p> <p><strong>基本信息 </strong></p> 英文名称： Anti-SMAD4 Polyclonal Antibody<br/>中文名称： SMAD家族成员4抗体<br/>规格： 100ul ; 50ul<br/>宿主： Rabbit<br/>克隆类型： Polyclonal Antibody<br/>亚型： IgG<br/>交叉反应：： Human<br/>应用： WB<br/>稀释比例： WB 1:500-2000.<p><strong>抗体信息 </strong></p> 靶标： SMAD4<br/>别名： DPC4;hSMAD4;JIP;MAD homolog 4;MADH4;Mothers against DPP homolog 4;SMAD 4;SMAD family member 4;SMAD4;MYHRS <br/>背景说明： This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.<br/>Swiss Prot： Q13485<br/>Gene ID： 4089<br/>亚细胞定位： Cytoplasm Nucleus<br/>免疫原： Recombinant protein of human SMAD4<br/>Public Immunogen Range： 27-392aa<br/>理论分子量： 60kDa<p><strong>其它标识 </strong></p> 纯化方法： Affinity purification<br/>储存液： PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.<br/>储存条件： Store at -20℃. Avoid freeze/thaw cycles. <p><strong>产品介绍 Product Introduction </strong></p> 使用前请离心。如有问题请及时联系我们。<br/>Quick spin before use. If you have any questions, please contact us. <p><strong>注意事项 Considerations </strong></p> 1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 <br/>2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 <br/>3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。